logo

        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name hsa-miR-34c-5p
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line human RB cell lines Y79 and SNUOT-Rb1
Methods microarray
Expression pattern up-regulated
Functional description There were 17 miRNAs, which were elevated in Y79 cells than SNUOT-Rb1 cells. More than half of top 10 mRNA targets of hsa-miR-34a, hsa-miR-34c-5p, hsa-miR-124, hsa-miR-135b, hsa-miR-142-5p, and hsa-let-7i in Y79 cells were related with biological processes, which could affect the growth patterns of cells: cell adhesion, cell cycle, cell death, and cell division.
PubMed ID 21941147
Year 2011
Title Differential profiles of microRNAs in retinoblastoma cell lines of different proliferation and adherence patterns.
Drug-related ncRNA NO

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.